Key result
Hypertensive patients demonstrated a significantly slower rate of left ventricular filling compared to normotensive subjects (P<0.05), suggesting diminished left ventricular compliance.
Why the study?
Do hypertensive patients have abnormal left ventricular relaxation compared to normotensive subjects?
Observational (n=27)
Do hypertensive patients have abnormal left ventricular relaxation compared to normotensive subjects?
Answers are grounded in this paper and cite their sources.
Hypertensive patients exhibit a slower rate of left ventricular filling, indicating diminished left ventricular compliance even when systolic function is preserved.
The maximum rates of left ventricular ejection and filling were derived (Fourier analysis) from the left ventricular volume curve (99m technetium-human serum albumin gated blood pool studies) in 12 normotensive subjects and 15 hypertensive patients of matched age groups. 2. Average values of cardiac output, ejection fraction, heart rate and left ventricular ejection rate were not significantly different in the two groups. 3. Hypertensive patients had a slower rate of left ventricular filling (P < 0.05), suggesting diminished left ventricular compliance in hypertension.
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Fouad et al. (1980) conducted an observational in Hypertension (n=27). Hypertension vs. Normotensive subjects was evaluated on Rate of left ventricular filling (p=<0.05). Hypertensive patients demonstrated a significantly slower rate of left ventricular filling compared to normotensive subjects (P<0.05), suggesting diminished left ventricular compliance.
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