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December 25, 2014Advances in Biomechanics and Applications

Coronary three vessel disease: hydrodynamic simulations including the time-dependence of the microvascular resistances

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Key result

Hydrodynamic simulations of the coronary network were updated to include the time-dependence of coronary microvascular resistances to better represent the effect of systolic ventricular contraction.

Population

Computational model of the coronary network with severe three-vessel coronary disease

Design

Other

Authors

MHMajid HarmoucheAAAmédéo AnselmiMMMahmoud Maasrani

Discussion

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Overview

May refine coronary flow simulations of systolic effects; leaves open clinical validation or perfusion assessment.

Structured PICO

P
Population
Computational model of the coronary network with severe three-vessel coronary disease (stenoses on left branches and total occlusion of the right coronary artery)
I
Intervention
Hydrodynamic simulations including time-dependence of coronary microvascular resistances to represent systolic ventricular contraction
O
Outcome
Simulation of fluxes and pressures in the coronary network

Incorporating time-dependent microvascular resistances into coronary hydrodynamic models may improve the simulation of systolic ventricular contraction effects on coronary blood flow.

Cite This Study

Harmouche et al. (2014) studied Coronary three vessel disease. Hydrodynamic simulations including time-dependence of coronary microvascular resistances was evaluated. Hydrodynamic simulations of the coronary network were updated to include the time-dependence of coronary microvascular resistances to better represent the effect of systolic ventricular contraction.

synapsesocial.com/papers/6a210669fd1130a429f6537dhttps://doi.org/10.12989/aba.2014.1.4.279
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