What question did this study set out to answer?

This commentary examines the balance between the benefits of single-use systems and their environmental consequences in the context of regulatory frameworks.

June 4, 2026PDA Journal of Pharmaceutical Science and Technology

Single-Use Systems between Compliance and Circularity: A Critical View under EU-GMP-Annex 1 and European Green Deal

View Full Paper

Ask AI

Bookmark

Authors

NHNicolas HuberEdelweiss Connect (Switzerland)

Discussion

Member takes

Implication

Commentary discusses single-use systems' performance and environmental impact, highlighting the need for optimized designs in pharmaceuticals.

Key Points

This commentary examines the balance between the benefits of single-use systems and their environmental consequences in the context of regulatory frameworks.
Analyzed current frameworks concerning EU-GMP-Annex 1 and the European Green Deal.
Reviewed life-cycle assessments of single-use systems versus stainless steel equipment.
Sought to address the complex challenges posed by plastic waste and resource management.
Single-use systems lower water, energy, and cleaning chemical use compared to stainless-steel equipment.
SUS contribute to climate change impact and resource depletion while generating difficult-to-recycle plastic waste.
Calls for a shift from a simple comparison to a broader perspective on application-specific optimization and material recovery.

Cite This Study

Nicolas Huber (2026) studied this question.

synapsesocial.com/papers/6a2115bdd499ed480b16ebc3 https://doi.org/10.5731/pdajpst.2026-000025.1

View Full Paper

Ask AI

Bookmark

Implication

Commentary discusses single-use systems' performance and environmental impact, highlighting the need for optimized designs in pharmaceuticals.

Single-Use Systems between Compliance and Circularity: A Critical View under EU-GMP-Annex 1 and European Green Deal

Discussion

Member takes

Implication

Key Points

Cite This Study

Single-Use Systems between Compliance and Circularity: A Critical View under EU-GMP-Annex 1 and European Green Deal

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider