Comprehensive review explores the interplay of circadian rhythms and obesity, highlighting clinical implications for cardiovascular health.
The intricate interplay among circadian rhythms, obesity, and cardiovascular diseases has garnered increasing attention in recent years. By examining how circadian rhythms regulate metabolic processes, appetite, and energy balance, the study sheds light on how disruptions to these rhythms contribute to the development of obesity and cardiovascular diseases. From the timing of food intake to the regulation of blood pressure and vascular function, circadian rhythms influence various physiological functions critical to health and overall wellbeing. Understanding this interplay not only provides insights into the underlying mechanisms of disease but also highlights the importance of aligning health behaviors to optimize metabolic and cardiovascular health. This exploration underscores the significance of chronobiology in preventive and therapeutic strategies, offering potential avenues for improving public health outcomes in an increasingly 24/7 society. Therefore, this comprehensive review aims to elucidate the multifaceted relationships between these factors, exploring the underlying mechanisms, clinical implications, and therapeutic strategies. This review will elucidate the role of circadian rhythms in metabolic regulation, adipose tissue function, vascular health, and cardiovascular physiology. Furthermore, it will also examine the bidirectional relationship between circadian disruption and the development of obesity and cardiovascular diseases, highlighting the importance of circadian alignment in preventive and therapeutic interventions.
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Fatima et al. (2026) studied this question.
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