January 1, 2010Circulation JournalOpen Access

Evaluation of Subclinical Right Ventricular Dysfunction in Obstructive Sleep Apnea Patients Using Velocity Vector Imaging

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Why the study?

Does velocity vector imaging and tissue Doppler imaging detect subclinical right ventricular dysfunction in patients with moderate-to-severe obstructive sleep apnea compared to healthy controls?

Population

53 participants, mean age 54±10 years, predominantly male. Key exclusions: systemic hypertension, mean PA…

Comparison

Evaluation of right ventricular function using… vs Healthy, BMI-matched control participants…

Design

Cross-sectional, All recordings and measurements were obtained by 2…

Authors

ATAylin TuğcuHealthwise ÖYÖzlem YıldırımtürkUniversity of Health Science YTYelda TayyareciIstanbul Florence Nightingale Hospital

Discussion

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Implication

VVI and TDI may detect subclinical RV dysfunction in OSA; hypothesis-generating for prognostic value and clinical relevance.

Structured PICO

Does velocity vector imaging and tissue Doppler imaging detect subclinical right ventricular dysfunction in patients with moderate-to-severe obstructive sleep apnea compared to healthy controls?

Population

53 participants (27 with moderate-to-severe obstructive sleep apnea [AHI ≥15 events/h] and 26 healthy BMI-matched controls), mean age 54±10 years, predominantly male (43/53). Key exclusions: systemic hypertension, mean PA pressure >25 mmHg, diabetes mellitus, LV ejection fraction <50%, coronary artery disease, and other significant comorbidities.

Intervention

Evaluation of right ventricular function using velocity vector imaging (VVI) and tissue Doppler imaging (TDI) in patients with moderate-to-severe obstructive sleep apnea

Comparator

Healthy, BMI-matched control participants without obstructive sleep apnea (AHI <5 events/h)

Outcome

Subclinical regional right ventricular (RV) dysfunction measured by VVI-derived peak systolic myocardial velocities, strain, and strain rate, and TDI-derived RV isovolumic acceleration (IVA)surrogate

Limitations

Small sample size
Possible gender differences cannot be established because the patients were predominantly males
Findings may not reflect the general community as systemic hypertension, diabetes mellitus, and coronary artery disease were excluded
Mean PA pressures were not corroborated by cardiac catheterization

Cite This Study

Tuğcu et al. (2010) studied this question.

synapsesocial.com/papers/6a211a2c38e3bbbbff02bc91 https://doi.org/10.1253/circj.cj-09-0562

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Evaluation of Subclinical Right Ventricular Dysfunction in Obstructive Sleep Apnea Patients Using Velocity Vector Imaging

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Evaluation of Subclinical Right Ventricular Dysfunction in Obstructive Sleep Apnea Patients Using Velocity Vector Imaging

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider