Key result
Moderate-severe obstructive sleep apnea was associated with a higher right ventricular myocardial performance index compared to mild OSA and controls (0.62 vs 0.50 and 0.48, P<0.001).
Why the study?
Does obstructive sleep apnea impair right ventricular global function as measured by myocardial performance index in uncomplicated patients?
Cross-Sectional (n=49)
Does obstructive sleep apnea impair right ventricular global function as measured by myocardial performance index in uncomplicated patients?
Absolute Event Rate: 0.62% vs 0.48%
p-value: p=<0.001
Moderate-severe obstructive sleep apnea is associated with right ventricular global and diastolic dysfunction even in the absence of other cardiopulmonary diseases.
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Indicates possible subclinical RV impairment in moderate-severe OSA without comorbidities; hypothesis-generating and should not yet change practice.
Dursunoğlu et al. (2005) conducted a cross-sectional in Obstructive sleep apnea (n=49). Moderate-severe obstructive sleep apnea vs. Control subjects (AHI <5) and mild OSA (AHI 5-14) was evaluated on Right ventricular myocardial performance index (MPI) (p=<0.001). Moderate-severe obstructive sleep apnea was associated with a higher right ventricular myocardial performance index compared to mild OSA and controls (0.62 vs 0.50 and 0.48, P<0.001).
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