Population
Chick embryos at Hamburger-Hamilton stage 27 following left atrial ligation at stage 21 to reduce LV volume…
Comparison
Left atrial ligation to alter mechanical load… vs Control chick embryo myocardial strips
Design
Preclinical
Authors
Loading...
Embryonic animal results should not yet change clinical practice; extends evidence for microtubules in adaptive myocardial stiffness during development.
Microtubules play a key role in the adaptive changes of myocardial material properties in response to altered mechanical load during embryonic heart development.
Schroder et al. (2002) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: