Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
April 1, 1999AJP Heart and Circulatory PhysiologyOpen Access

VSE and R-R interval had r2 values of 0.847 and 0.852, respectively, best satisfying the criteria for the ideal index of sympathovagal balance.

View Full Paper
Ask AI
Bookmark
Share

Population

14 volunteers (8 men, 6 women; mean age 28.5 +/- 4.8 yr)

Design

Other

Authors

JGJeffrey J. Goldberger

Discussion

Loading...

Member takes

Overview

Supports VSE and R-R interval as preferred sympathovagal indexes; leaves open prospective outcome validation before clinical adoption.

Key Points

  • The aim is to evaluate heart rate and heart rate variability as measures of sympathovagal balance and identify an ideal parameter.
  • Evaluated 14 volunteers (8 men and 6 women) with a mean age of 28.5 years for sympathetic and parasympathetic effects on heart rate and variability.
  • Defined vagal-sympathetic effect (VSE) as the ratio of R-R interval to intrinsic R-R interval.
  • Utilized a general linearized model to assess responses of parameters.
  • VSE and R-R interval showed strong correlation with r2 values of 0.847 and 0.852, respectively.
  • Natural logarithm of low-frequency power had r2 value of 0.781 with lower values in other parameters.
  • Coefficient of variation for VSE and R-R interval was the lowest across tested conditions.

Structured PICO

P
Population
14 volunteers (8 men, 6 women; mean age 28.5 +/- 4.8 yr)
I
Intervention
Sympathetic and parasympathetic stimulation and blockade
O
Outcome
Utility of HR, HR variability, and vagal-sympathetic effect (VSE) as indexes of sympathovagal balancesurrogate

The R-R interval and the novel vagal-sympathetic effect (VSE) parameter are the most suitable indexes of sympathovagal balance compared to traditional heart rate variability parameters.

Cite This Study

Jeffrey J. Goldberger (1999) studied this question.

synapsesocial.com/papers/6a212644f69db56553c3be37https://doi.org/10.1152/ajpheart.1999.276.4.h1273
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Heart rate and heart rate variability as indexes of sympathovagal balance1994 · 249 citations
  2. 2To the interpretation of frequency components of the heart rate variability2022 · 3 citations
  3. 3Sympathovagal balance is major determinant of short-term blood pressure variability in healthy subjects1999 · 132 citations
  4. 4A Novel Index of Sympathovagal Balance From Independent Component Analysis of Heart Rate and Blood Pressure Variability: Performance in Patients With Carotid Stenting and in the EuroBavar Data Set2011
  5. 5Assessment of Sympathovagal Imbalance By Spectral Analysis of Heart Rate Variability in Prehypertensive and Hypertensive Patients in Indian Population2011 · 61 citations