Why the study?
Does insulin-mediated muscle blood flow correlate with glucose uptake during sustained hyperinsulinaemia in healthy subjects?
Population
13 healthy subjects
Comparison
4-hour insulin infusion using the euglycaemic… vs Baseline measurements prior to insulin infusion
Design
Other
Follow-up
4 hours
Authors
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May implicate vascular mechanisms in insulin sensitivity; leaves open relevance to insulin-resistant states or therapy.
Does insulin-mediated muscle blood flow correlate with glucose uptake during sustained hyperinsulinaemia in healthy subjects?
Insulin-mediated muscle blood flow strongly correlates with glucose uptake during sustained hyperinsulinaemia, suggesting haemodynamic effects are important contributors to its metabolic actions.
Maaten et al. (1998) studied this question.
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