Why the study?
Does deoxycorticosterone acetate-salt hypertension alter cardiac contractile and coronary flow reserves in conscious rats?
Does deoxycorticosterone acetate-salt hypertension alter cardiac contractile and coronary flow reserves in conscious rats?
In a rat model of DOCA-salt hypertension, cardiac contractile function and coronary flow reserves are preserved despite the development of left ventricular hypertrophy and structural coronary vascular changes.
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Supports vascular adaptation in experimental LVH; leaves open whether coronary reserves remain intact in patients with hypertension.
Yamamoto et al. (1985) studied this question.
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