Why the study?
Does the T allele of the TGF-beta1 gene increase susceptibility to myocardial infarction in a Japanese population?
Population
906 Japanese subjects, comprising 315 patients with myocardial infarction and 591 control subjects.
Comparison
Presence of the T allele at nucleotide 29 of the… vs CC genotype at nucleotide 29 of the TGF-beta1 gene
Design
Case-control
Authors
Loading...
May support sex-specific genetic risk assessment in Japanese men; leaves open prospective validation before clinical use.
Does the T allele of the TGF-beta1 gene increase susceptibility to myocardial infarction in a Japanese population?
The T allele at nucleotide 29 in the TGF-beta1 gene is associated with an increased risk of myocardial infarction in Japanese men.
Yokota et al. (2000) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: