Key result
Resting muscle sympathetic nerve activity burst frequency was negatively correlated with sympathetic transduction of blood pressure (r = -0.42; P < 0.01) and transduction slope (r = -0.66; P < 0.01).
Why the study?
Calculating sympathetic transduction of blood pressure may be influenced by an individual's resting muscle sympathetic nerve activity burst frequency.
Cross-Sectional (n=107)
Effect estimate: r = -0.42
p-value: p=<0.01
Incorporating MSNA burst frequency into the calculation of sympathetic transduction of blood pressure accounts for prevailing resting burst frequency, allowing for more accurate comparisons between individuals.
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Higher MSNA burst frequency associates with lower BP transduction; leaves open whether burst-frequency adjustment refines autonomic phenotyping in future studies.
Nardone et al. (2021) conducted a cross-sectional in Healthy (n=107). Resting muscle sympathetic nerve activity (MSNA) burst frequency vs. Low vs high MSNA was evaluated on Correlation between MSNA burst frequency and sympathetic transduction of BP (r = -0.42, p=<0.01). Resting muscle sympathetic nerve activity burst frequency was negatively correlated with sympathetic transduction of blood pressure (r = -0.42; P < 0.01) and transduction slope (r = -0.66; P < 0.01).
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