Key result
Cohort-averaged 3D wall thickness maps showed a significant negative spatial correlation with wall shear stress (Spearman's ρ -0.56), enabling the prediction of individual wall thickness.
Why the study?
Can 3D wall thickness maps be predicted from individual 3D wall shear stress and diameter maps in patients with asymptomatic carotid atherosclerosis?
Population
20 subjects with asymptomatic plaques in the left carotid artery, retrospectively selected from the…
Design
Cross-sectional
Authors
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May guide WSS-based imaging biomarkers in carotid atherosclerosis; leaves open reliable patient-specific prediction and clinical utility.
Cross-Sectional (n=20)
No
Can 3D wall thickness maps be predicted from individual 3D wall shear stress and diameter maps in patients with asymptomatic carotid atherosclerosis?
Effect estimate: Spearman's ρ -0.56 (95% CI -0.74, -0.38)
3D cohort-averaging of MRI data reveals significant spatial correlations between low wall shear stress and increased wall thickness in asymptomatic carotid atherosclerosis, allowing for patient-specific wall thickness prediction.
Ooij et al. (2018) conducted a cross-sectional in Asymptomatic atherosclerotic carotid bifurcations (n=20). MRI-derived wall shear stress and vessel diameter was evaluated on Spatial correlation between cohort-averaged wall thickness and wall shear stress (Spearman's ρ -0.56, 95% CI -0.74, -0.38). Cohort-averaged 3D wall thickness maps showed a significant negative spatial correlation with wall shear stress (Spearman's ρ -0.56), enabling the prediction of individual wall thickness.
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