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This research aims to quantify the plasma levels of epinephrine and norepinephrine during different types of shock in dogs.

Plasma Concentration of Epinephrine and Norepinephrine in Hemorrhagic and Anaphylactic Shock

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Fluorometric quantification of plasma pressor amines reveals significant changes during shock in dogs, indicating stress response mechanisms.

This research aims to quantify the plasma levels of epinephrine and norepinephrine during different types of shock in dogs.
Used a fluorometric method to analyze plasma before and after hemorrhage in four anesthetized dogs.
Examined seven sensitized dogs after administration of egg white to induce anaphylactic shock.
Administered histamine to observe changes in plasma pressor amines.
Epinephrine concentration increased from 1.0 to 7.8 µg/L after significant blood loss, while norepinephrine levels went from 2.5 to 3.6 µg/L.
During anaphylactic reactions, epinephrine levels rose from 0.7 to 7.7 µg/L; norepinephrine levels were variable.
Histamine administration resulted in hypotension with slight increases in plasma pressor amines.

Manger et al. (1957) studied this question.

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Fluorometric quantification of plasma pressor amines reveals significant changes during shock in dogs, indicating stress response mechanisms.