November 1, 1983Hypertension

Basal levels of plasma epinephrine and norepinephrine in the dog.

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Population

96 dogs (62 conscious, 34 anesthetized)

Comparison

Acclimatization to laboratory conditions for at… vs Conscious dogs sampled soon after arrival to the…

Design

Preclinical

Authors

PBP A Bridle KBK. Bridget BrosnihanAtrium Health Wake Forest Baptist RSRobert C. SpethHeart Failure & Transplant

Discussion

Member takes

Implication

Standardization of acclimatization required for valid catecholamine assessment in dogs; leaves open translation to human sympathetic indices in hypertension.

Structured PICO

Population

96 dogs (62 conscious, 34 anesthetized)

Intervention

Acclimatization to laboratory conditions for at least 15 minutes prior to blood sampling (in conscious dogs) or anesthesia with one of three regimes

Comparator

Conscious dogs sampled soon after arrival to the laboratory

Outcome

Basal levels of plasma epinephrine (E) and norepinephrine (NE)surrogate

Standardizing conditions for sample collection is necessary when using catecholamine levels as an index of sympathetic nervous system activity in dogs due to significant variability based on acclimatization.

Cite This Study

Bridle et al. (1983) studied this question.

synapsesocial.com/papers/6a945d3229dbf9896b7076dc https://doi.org/10.1161/01.hyp.5.6_pt_3.v128

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Implication

Standardization of acclimatization required for valid catecholamine assessment in dogs; leaves open translation to human sympathetic indices in hypertension.

Basal levels of plasma epinephrine and norepinephrine in the dog.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Basal levels of plasma epinephrine and norepinephrine in the dog.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider