Why the study?
Do circulating catecholamine levels adequately reflect the degree of inotropic stimulation to the myocardium in conscious dogs?
Population
Conscious dogs instrumented for the measurement of left ventricular and arterial pressures, LV diameter, and…
Comparison
1) Infusions of norepinephrine and epinephrine… vs Comparison between different physiological states
Design
Preclinical
Authors
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May caution against equating plasma catecholamines with inotropy; leaves open local sympathetic contributions in exercise and stress models.
Do circulating catecholamine levels adequately reflect the degree of inotropic stimulation to the myocardium in conscious dogs?
Circulating catecholamine levels do not adequately reflect the degree of inotropic stimulation to the myocardium during exercise, hemorrhage, or catecholamine infusion in conscious dogs.
Young et al. (1985) studied this question.
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