Key result
A mathematical model with well-characterized structural and biochemical actomyosin states successfully reproduced a wide range of contractile phenomena from single motor molecules to muscle.
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Advances multiscale actomyosin modeling; leaves open validation and translation to human cardiac function.
Alf Månsson (2016) studied Muscle contraction. Mathematical model of actomyosin contraction was evaluated. A mathematical model with well-characterized structural and biochemical actomyosin states successfully reproduced a wide range of contractile phenomena from single motor molecules to muscle.
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