Key result
Human fetal cardiac myofibrils exhibit low specific force and slow activation and relaxation kinetics early in gestation, which progressively increase between 8 and 19 weeks of gestation.
Authors
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Informs fetal cardiac development models; extends animal data but leaves open clinical correlations.
Racca et al. (2015) studied Human fetal cardiac muscle development. Gestational age (8-19 weeks) was evaluated on Contractile properties (specific force, rates of force development and relaxation). Human fetal cardiac myofibrils exhibit low specific force and slow activation and relaxation kinetics early in gestation, which progressively increase between 8 and 19 weeks of gestation.
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