Key result
Decreased circumferential strain was significantly associated with incident heart failure (HR per SD increment 1.79; 95% CI 1.35-2.37; P<0.0001) in a community-based cohort.
Why the study?
Do distinct components of LV mechanical function measured by speckle tracking echocardiography predict incident CHD, HF, and all-cause mortality in a community-based population?
Cohort (n=2,831)
Do distinct components of LV mechanical function measured by speckle tracking echocardiography predict incident CHD, HF, and all-cause mortality in a community-based population?
Hazard Ratio: 1.79 (95% CI 1.35–2.37)
p-value: p=<0.0001
Distinct components of LV mechanical function, particularly circumferential strain, provide independent prognostic information for incident heart failure and all-cause mortality in a community-based population.
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May enhance community HF risk stratification; leaves open incremental value over standard factors for practice.
Cheng et al. (2015) conducted a cohort in Cardiovascular disease (n=2,831). Left ventricular mechanical function (LV strain) vs. Per standard deviation increment was evaluated on Incident heart failure (HR 1.79, 95% CI 1.35-2.37, p=<0.0001). Decreased circumferential strain was significantly associated with incident heart failure (HR per SD increment 1.79; 95% CI 1.35-2.37; P<0.0001) in a community-based cohort.
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