What question did this study set out to answer?

To investigate the prevalence and prognostic implications of depression in patients with unstable angina.

May 8, 2000Archives of Internal Medicine

Depression and 1-Year Prognosis in Unstable Angina

View Full Paper

Ask AI

Bookmark

Why the study?

Does depression increase the risk of 1-year cardiac death or nonfatal myocardial infarction in patients with unstable angina?

Population

430 patients with unstable angina who did not require coronary artery bypass surgery before hospital discharge

Comparison

Depression vs No depression

Design

Cohort

Follow-up

1 year

Authors

FLFrançois LespérancePreventive Cardiology NFNancy Frasure‐SmithPreventive Cardiology MJMartin JuneauPreventive Cardiology

Discussion

Member takes

Implication

May warrant depression screening in unstable angina; leaves open whether treatment modifies cardiac outcomes.

Key Points

To investigate the prevalence and prognostic implications of depression in patients with unstable angina.
Interviews with 430 patients having unstable angina who did not undergo coronary artery bypass surgery
Depression assessed using the Beck Depression Inventory with a cutoff score of 10
Primary outcome measured was 1-year cardiac death or nonfatal myocardial infarction.
41.4% of patients were identified as depressed using the Beck Depression Inventory.
Depressed patients had a 4.68 times higher likelihood of experiencing cardiac death or nonfatal myocardial infarction (95% CI, 1.94-11.27; P<.001).
After adjusting for other factors, the odds ratio for cardiac events in depressed patients was 6.73 (95% CI, 2.43-18.64; P<.001).

Structured PICO

Does depression increase the risk of 1-year cardiac death or nonfatal myocardial infarction in patients with unstable angina?

Population

430 patients with unstable angina who did not require coronary artery bypass surgery before hospital discharge

Intervention

Depression (defined as a score of 10 or higher on the 21-item self-report Beck Depression Inventory)

Comparator

No depression (Beck Depression Inventory score <10)

Outcome

1-year cardiac death or nonfatal myocardial infarctioncomposite

Depression is highly prevalent in patients with unstable angina and serves as a strong, independent predictor of major adverse cardiac events at 1 year.

Cite This Study

Lespérance et al. (2000) studied this question.

synapsesocial.com/papers/6a21752ac2e34e33095fabdd https://doi.org/10.1001/archinte.160.9.1354

View Full Paper

Ask AI

Bookmark

Depression and 1-Year Prognosis in Unstable Angina

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Depression and 1-Year Prognosis in Unstable Angina

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider