Key result
Fibre stiffness was consistently lower at an extended sarcomere length of 2.60 microm compared to 2.20 microm, with the stiffness ratio ranging from 0.83 to 0.97 at different loads.
Effect estimate: Ratio 0.83 to 0.97
The study demonstrates non-linear myofilament elasticity in frog intact muscle fibres, with stiffness increasing progressively as load increases.
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Frog fibre data warrant caution in extrapolation; leaves open length-dependent stiffness mechanisms in mammalian myocardium.
K. A. P. Edman (2009) studied this question. Extended sarcomere length (2.60 microm) vs. Full overlap sarcomere length (2.20 microm) was evaluated on Instantaneous fibre stiffness (Ratio 0.83 to 0.97). Fibre stiffness was consistently lower at an extended sarcomere length of 2.60 microm compared to 2.20 microm, with the stiffness ratio ranging from 0.83 to 0.97 at different loads.
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