Key result
During steady lengthening of frog muscle fibres, cross-bridge number rises to 1.8 times the isometric value, and after-stretch potentiation is explained by a residual larger cross-bridge number.
Population
tetanized single muscle fibres from Rana temporaria (4 C; 2.15 micrometer sarcomere length)
Comparison
steady lengthening at approximately 160 nm s(-1) vs isometric tetanus plateau (To)
Design
Preclinical
Authors
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Hypothesis-generating for eccentric muscle mechanics; leaves open translation to mammalian or human physiology.
The study demonstrates that after-stretch potentiation in frog muscle fibers is explained by a residual larger cross-bridge number, with structural data supporting mechanical findings.
Linari et al. (2000) studied this question. Steady lengthening vs. Isometric tetanus plateau was evaluated on Intensity of the third order myosin meridional X-ray reflection (IM3) and stiffness. During steady lengthening of frog muscle fibres, cross-bridge number rises to 1.8 times the isometric value, and after-stretch potentiation is explained by a residual larger cross-bridge number.
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