Population
Isolated frog muscle fibres
Comparison
Steady lengthenings at different velocities… vs Isometric conditions
Design
Preclinical
Authors
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Advances cross-bridge mechanics in amphibian lengthening; leaves open validation in mammalian or human muscle.
This study elucidates the mechanical behavior of cross-bridges in frog muscle fibers during steady lengthening, showing that high-speed lengthening increases cross-bridge extension.
Piazzesi et al. (1992) studied this question.