Tension transients during steady shortening of frog muscle fibres.
Population
Single intact fibres from frog muscle at 0-1 degrees C
Design
Preclinical
Authors
Discussion
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Member takes
Implication
Findings in frog fibers do not alter clinical practice; extends cross-bridge models but leaves open translation to human cardiac muscle.
Structured PICO
P
Population
Single intact fibres from frog muscle at 0-1 degrees C
I
Intervention
Step and ramp length changes (shortening) during isometric tetani
O
Outcome
Tension transients (T1, T2) and stiffness during shorteningsurrogate
In frog muscle fibers, stiffness during shortening decreases linearly with tension, suggesting a reduced number of attached cross-bridges as shortening velocity increases.
Cite This Study
Ford et al. (1985) studied this question.