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Age influences the intensity of lipid peroxidation and antioxidant protection during postinfarction heart remodeling in a rat model.
Results of research of a state of lipid peroxidation (LP) system at rats by age of 4 and 12 months with postinfarction cardiosclerosis are presented in this work. It has been shown, that in the remote terms after an experimental myocardium infarct, age-dependent alteration of the LP and antioxidizing enzymes activity were observed. Also distinction in expressiveness of the LP processes in the intact animals in these age groups was revealed. Such age features probably cause various intensities of the LP and the state of antioxidant protection at postinfarction remodeling of heart.
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Rebrova et al. (2011) studied this question.
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