Key result
Hypertension was significantly associated with chronic pain (OR 1.039; 95% CI 1.018-1.060; P<0.0001), whereas prehypertension was not.
Why the study?
Studies in developing countries linking chronic pain and hypertension are scarce, and the association between pain and prehypertension is rarely explored.
Is there an association between chronic pain and prehypertension or hypertension in adults?
Cross-Sectional (n=1,031)
Is there an association between chronic pain and prehypertension or hypertension in adults?
In a Saudi population, chronic pain is significantly associated with hypertension but not prehypertension.
Answers are grounded in this paper and cite their sources.
Association with hypertension but not prehypertension is hypothesis-generating; prospective studies needed before clinical implications.
Background: Chronic pain and hypertension are highly prevalent in both developing and developed countries. Although they may appear to be two separate phenomena, several studies in developed countries have found them associated at the population level. Studies in developing countries are scarce and association between pain with prehypertension are rarely explored. The objective of this study was to explore the potential association between prehypertension, hypertension, and chronic pain in a Saudi population.Methods: A cross-sectional general population-based study was conducted on a random sample of employees and university students over a period of 6 months from January 2016 to June 2016 in Al Kharj, Saudi Arabia. A total of 1200 general population adults (aged 18 years and above) were invited to participate in the study.Results: With a response rate of 85.9%, 1031 individuals were included in the final analysis. Among the general population of Al-Kharj, statistically significant association was found between age and chronic pain [Odds ratio (OR) = 1.764 [95% C.I. = 1.391–1.927], P < 0.0001] and between hypertension and chronic pain [(OR) = 1.039 [95% C.I. = 1.018–1.060], P < 0.0001], respectively. The association between prehypertension and chronic pain was not statistically significant [(OR) = 1.211 [95% C.I. = 0.879–1.668, P = 0.243].Conclusion: Results of this survey suggests a statistically significant relationship between hypertension (but not prehypertension) and chronic pain. The temporality of the relationship between hypertension and chronic needs to be explored in future longitudinal studies.
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Al‐Ghamdi et al. (2020) conducted a cross-sectional in Chronic pain and hypertension (n=1,031). Hypertension vs. No hypertension was evaluated on Chronic pain (OR 1.039, 95% CI 1.018-1.060, p=< 0.0001). Hypertension was significantly associated with chronic pain (OR 1.039; 95% CI 1.018-1.060; P<0.0001), whereas prehypertension was not.
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