Key result
This review describes the mechanisms of ROS-mediated oxidative stress in cardiovascular disease, particularly induced by oncological treatments, and discusses strategies to counteract it.
Why the study?
In pathological conditions, reactive oxygen species production exceeds cellular antioxidant capacity, contributing to cellular damage and cardiovascular disease induced by oncological treatments.
Design
Review
Authors
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ROS mechanisms in cardio-oncology merit targeted study; leaves open validation of counteracting strategies in trials.
This review summarizes the mechanisms of ROS-mediated oxidative stress in cardiovascular disease, particularly in the context of cardio-oncology, and discusses potential counteracting strategies.
Sabbatino et al. (2021) conducted a review in Cardiovascular disease in cancer patients. This review describes the mechanisms of ROS-mediated oxidative stress in cardiovascular disease, particularly induced by oncological treatments, and discusses strategies to counteract it.
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