Key result
Targeted biological cancer therapies, including anti-HER2 agents and VEGF inhibitors, can induce cardiotoxicity such as left ventricular dysfunction and hypertension, necessitating regular cardiologic follow-up.
Biological cancer therapies can cause significant cardiovascular side effects, necessitating regular cardiologic monitoring and a multidisciplinary cardio-oncology approach.
Supports cardio-oncology integration in cancer care; leaves open optimal surveillance protocols pending prospective data.
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Ivo Darko Gabrić (2017) conducted a review in Cancer. Biological cancer therapy (monoclonal antibodies and tyrosine kinase inhibitors) was evaluated. Targeted biological cancer therapies, including anti-HER2 agents and VEGF inhibitors, can induce cardiotoxicity such as left ventricular dysfunction and hypertension, necessitating regular cardiologic follow-up.
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