Key result
Children with respiratory distress had significantly higher mean serum troponin T levels compared to controls (0.02468 vs 0.02171 ng/ml), which correlated positively with respiratory severity.
Why the study?
Cardiac complications can occur in acute pediatric respiratory diseases, and the study aimed to detect cardiac affection using troponin T in children with acute chest diseases and correlate it with the Pediatric Respiratory Severity Score.
Does serum troponin T level correlate with respiratory distress severity (PRESS) in children with acute chest diseases?
Case-Control (n=250)
Does serum troponin T level correlate with respiratory distress severity (PRESS) in children with acute chest diseases?
Answers are grounded in this paper and cite their sources.
Troponin T elevation may signal cardiac strain in severe pediatric respiratory distress; confirms correlation with severity but leaves clinical utility open.
Background Respiratory distress owing to pulmonary causes is the most common cause of visits to the pediatric emergency departments. Cardiac complications are reported to occur in acute respiratory tract diseases such as myocarditis, pericarditis, heart failure, myocardial infarction, and arrhythmia. Serum troponin T is a cardiospecific and sensitive biomarker with a diagnostic and prognostic significance for myocardial damage.Objective The aim was to detect cardiac affection using troponin T in children with acute chest diseases and correlate it with Pediatric Respiratory Severity Score (PRESS).Patients and methods A case–control study was conducted, including 150 children with respiratory distress selected from the emergency department (6 month to 12 years of age) and 100 (age and sex matched) controls. Respiratory distress severity was clinically assessed using PRESS. Cardiac troponin T levels were assayed using enzyme-linked immunosorbent assay and compared with controls. Troponin T levels were correlated with PRESS.Results Mean troponin T serum levels had significantly higher levels in children with respiratory distress compared with controls (mean value 0.02468±0.01310 and 0.02171±0.00663 ng/ml, respectively). It correlated positively with PRESS score, especially in patients with pneumonia.Conclusion Serum troponin T level correlates with PRESS, and cardiac injury can worsen respiratory distress in children with acute chest diseases, especially in pneumonia.
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Ishak et al. (2020) conducted a case-control in acute chest diseases and respiratory distress (n=250). Acute chest diseases with respiratory distress vs. Age and sex matched controls was evaluated on Mean troponin T serum levels (ng/ml). Children with respiratory distress had significantly higher mean serum troponin T levels compared to controls (0.02468 vs 0.02171 ng/ml), which correlated positively with respiratory severity.
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