Key result
Urinary angiotensinogen excretion was significantly positively correlated with left ventricular mass index (r=0.724, p=0.012) and carotid intima-media thickness (r=0.452, p=0.02) in hypertensive RTRs.
Cross-Sectional (n=96)
Effect estimate: r = 0.724 for LVMI; r = 0.452 for CIMT
p-value: p = 0.012 for LVMI; p = 0.02 for CIMT
Urinary angiotensinogen excretion is positively correlated with left ventricular mass index and carotid intima-media thickness in hypertensive renal transplant recipients, suggesting a role for local intrarenal RAS in cardiovascular abnormalities.
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Urinary angiotensinogen may flag higher cardiovascular risk in hypertensive RTRs; hypothesis-generating and should not yet change practice.
Tiryaki et al. (2015) conducted a cross-sectional in Hypertensive kidney transplant recipients (n=96). Urinary angiotensinogen excretion rates vs. Normotensive patients was evaluated on Left ventricular mass index (LVMI) and carotid intima-media thickness (CIMT) (r = 0.724 for LVMI; r = 0.452 for CIMT, p=p = 0.012 for LVMI; p = 0.02 for CIMT). Urinary angiotensinogen excretion was significantly positively correlated with left ventricular mass index (r=0.724, p=0.012) and carotid intima-media thickness (r=0.452, p=0.02) in hypertensive RTRs.
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