Key result
Dopamine infusion during hyperoxia had no progressive effect on ventilation or end-tidal PCO2 with ventilatory acclimatization to high altitude.
Why the study?
Does dopamine infusion alter ventilation and end-tidal PCO2 in hyperoxia following ventilatory acclimatization to altitude?
Does dopamine infusion alter ventilation and end-tidal PCO2 in hyperoxia following ventilatory acclimatization to altitude?
The carotid body does not appear to play a role in generating the persistent hyperventilation that remains in hyperoxia after ventilatory acclimatization to altitude.
No takes yet. Share an insight, caveat, or question.
No dopamine effect on post-acclimatization hyperventilation in hyperoxia; leaves open carotid body-independent mechanisms for further study.
Pedersen et al. (2000) studied Ventilatory acclimatization to high altitude (n=8). Dopamine vs. Hyperoxia without dopamine was evaluated on Ventilation and end-tidal PCO2. Dopamine infusion during hyperoxia had no progressive effect on ventilation or end-tidal PCO2 with ventilatory acclimatization to high altitude.
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