Key result
HFpEF links to limited exercise ventilatory reserve, driven by smaller lung capacity and upper body adiposity.
Why the study?
Patients with HFpEF exhibit a tachypneic breathing strategy during exercise, but whether they have limited ventilatory reserve compared with controls and whether greater upper body adiposity contributes remain unknown.
Do patients with HFpEF have limited ventilatory reserve compared with control patients during exercise, and does greater upper body adiposity contribute to this limitation?
Population
16 patients with HFpEF and 19 control patients
Comparison
Patients with HFpEF vs control patients
Authors
Loading...
May refine HFpEF exercise testing interpretation; hypothesis-generating for adiposity-targeted interventions.
Observational (n=35)
Do patients with HFpEF have limited ventilatory reserve compared with control patients during exercise, and does greater upper body adiposity contribute to this limitation?
Patients with HFpEF have limited ventilatory reserve during exercise, which is partly driven by smaller lung capacity associated with greater upper body adiposity.
Cifci et al. (2025) conducted an observational in Heart failure with preserved ejection fraction (n=35). Heart failure with preserved ejection fraction vs. Control patients was evaluated on Ventilatory reserve during exercise. Patients with HFpEF had limited ventilatory reserve during exercise compared to controls, partly due to smaller lung capacity and greater upper body adiposity.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: