Key result
Orthostatic syncope provoked by tilting and nitroglycerin significantly increased plasma adrenaline concentrations from 19.2 to 104.3 pg/ml on average (P<0.01) in healthy men.
Why the study?
Does orthostatic syncope during tilting affect plasma adrenaline and noradrenaline levels in healthy men?
Does orthostatic syncope during tilting affect plasma adrenaline and noradrenaline levels in healthy men?
Absolute Event Rate: 104.3% vs 19.2%
p-value: p=<0.01
Orthostatic syncope provoked by tilt and nitroglycerin is associated with a significant increase in plasma adrenaline, but not a differential noradrenaline response.
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Adrenaline surge in provoked syncope may inform mechanisms; leaves open diagnostic or prognostic value in patients.
Tatár et al. (1986) studied Healthy (n=7). Tilt testing with sublingual nitroglycerin vs. Tilting without collapse / Baseline was evaluated on Plasma adrenaline concentrations (p=<0.01). Orthostatic syncope provoked by tilting and nitroglycerin significantly increased plasma adrenaline concentrations from 19.2 to 104.3 pg/ml on average (P<0.01) in healthy men.
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