The hemodynamics in young patients with borderline hypertension.
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Key result
Borderline hypertension in young patients was associated with significantly increased total peripheral resistance compared to normotensive controls (p<0.005).
Population
112 young subjects, comprising 56 patients with borderline hypertension and 56 age-matched normotensive…
Design
Case-control
Authors
Discussion
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Implication
May inform early hemodynamic evaluation in young borderline hypertension; leaves open neurogenic mechanisms and therapeutic targets.
Study Design
Type
Cross-Sectional (n=112)
Structured PICO
P
Population
112 young subjects, including 56 with borderline hypertension and 56 age-matched normotensive controls, assessed for supine hemodynamics.
C
Comparator
Age-matched normotensive subjects
O
Outcome
Hemodynamics in supine position studied echocardiographically, specifically cardiac index (CI) and total peripheral resistance (TPR)surrogate
Main Result
p-value: p=<0.005
Young patients with borderline hypertension exhibit abnormal total peripheral resistance and can be divided into distinct hemodynamic subgroups, suggesting impaired neurogenic activity in the early stages of hypertension.
Cite This Study
Fujita et al. (1983) conducted a cross-sectional in Borderline hypertension (n=112). Borderline hypertension vs. Normotensive subjects was evaluated on Total peripheral resistance (TPR) (p=<0.005). Borderline hypertension in young patients was associated with significantly increased total peripheral resistance compared to normotensive controls (p<0.005).
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