August 1, 1974Clinical Science
Cardiopulmonary Blood Volume in Borderline Hypertension
Why the study?
Does cardiopulmonary blood volume and haemodynamic profile differ between borderline and permanent hypertension?
Population
33 patients, comprising 17 with borderline hypertension and 16 with permanent hypertension.
Comparison
Haemodynamic assessment including estimation of… vs Permanent hypertensive patients.
Design
Cross-sectional
Authors
Discussion
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Implication
Supports volume redistribution in borderline hypertension; leaves open mechanistic distinctions from permanent hypertension and clinical relevance.
Structured PICO
Does cardiopulmonary blood volume and haemodynamic profile differ between borderline and permanent hypertension?
P
Population
33 patients, comprising 17 with borderline hypertension and 16 with permanent hypertension.
I
Intervention
Haemodynamic assessment including estimation of cardiopulmonary blood volume (CPBV), total blood volume (TBV), and vascular reactivity to noradrenaline.
C
Comparator
Permanent hypertensive patients (compared against borderline hypertensive patients).
O
Outcome
Cardiopulmonary blood volume (CPBV), total blood volume (TBV), CPBV/TBV ratio, and haemodynamic parameters (cardiac index, stroke index, heart rate, blood pressure, total peripheral resistance).surrogate
Borderline hypertension is associated with a redistribution of intravascular volume to the cardiopulmonary bed and a neural mechanism, whereas permanent hypertension relates to a volume mechanism.
Cite This Study
Safar et al. (1974) studied this question.