Key result
White coat hypertension in men with cardiovascular risk factors was associated with significantly higher mortality compared to normotension (33.3% vs 9.5%; adjusted RR 3.3, 95% CI 1.2-7.6).
Why the study?
Does white coat hypertension or a large white coat effect predict mortality in men with cardiovascular risk factors?
Population
536 men with cardiovascular risk factors at baseline
Comparison
White coat hypertension or a large white coat… vs Normotensive men (n=259)
Design
Cohort
Follow-up
21 years
Authors
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May warrant closer monitoring in high-risk men; leaves open whether intervention improves outcomes in this observational cohort.
Cohort (n=536)
Does white coat hypertension or a large white coat effect predict mortality in men with cardiovascular risk factors?
Relative Risk: 3.3 (95% CI 1.2–7.6)
Absolute Event Rate: 33.3% vs 9.5%
p-value: p=0.0005
White coat hypertension and a large white coat effect are not benign, as they are associated with metabolic risk factors and predict long-term total and cardiovascular mortality.
Timo Strandberg (2000) conducted a cohort in Cardiovascular risk factors (n=536). White coat hypertension vs. Normotension was evaluated on Mortality (RR 3.3, 95% CI 1.2-7.6, p=0.0005). White coat hypertension in men with cardiovascular risk factors was associated with significantly higher mortality compared to normotension (33.3% vs 9.5%; adjusted RR 3.3, 95% CI 1.2-7.6).
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