Key result
Being physically active (OR 3.8; 95% CI 1.3-11.5) and frequent program attendance (OR 2.7; 95% CI 1.2-5.9) were associated with significant improvements in 6-minute walk distance at 12 weeks.
Why the study?
Exercise training is recommended for stable HF but adherence is poor, and the relationship between exercise participation and 6MWD improvement needed investigation in recently hospitalized patients.
Does frequent exercise training program attendance and physical activity participation improve 6-min walk distance in recently hospitalized heart failure patients?
Cohort (n=140)
Does frequent exercise training program attendance and physical activity participation improve 6-min walk distance in recently hospitalized heart failure patients?
Odds Ratio: 3.8 (95% CI 1.3–11.5)
Attaining 150 minutes of moderate-intensity exercise per week and frequent program attendance significantly improves 6-minute walk distance in recently hospitalized heart failure patients.
Supports activity and attendance emphasis in post-HF hospitalization rehab; hypothesis-generating, needs RCTs to confirm causality.
Background: Exercise training is recommended for all people with stable heart failure (HF) however adherence is poor. This study sought to describe exercise participation in recently hospitalized HF patients who participated in a 12-week exercise training program. The association between exercise training variables and improvement in 6-min walk distance (6MWD) was also investigated.Methods: This study is a secondary analysis of results from the intervention arm of the EJECTION-HF trial (ACTRN12608000263392), (n = 140). Exercise program attendance was defined according to session frequency (< 12 sessions vs ≥ 12 sessions) and attendance duration (< 6 weeks attendance vs ≥ 6 weeks) over the 12 weeks. Physical activity at baseline and follow up were reported according to self-report of 150 min of moderate intensity exercise per week. Primary outcome was change in 6MWD at 12 weeks.Results: Being physically active (OR 3.8, CI 1.3–11.5) and frequent program attendance (OR 2.7, CI 1.2–5.9) were associated with significant improvements in 6MWD. Program duration and baseline physical activity were not significantly associated with the outcome.Conclusions: Attainment of 150 min of moderate intensity exercise per week and at least weekly attendance at the program, were associated with significant improvements in 6MWD at follow up. Efforts should be made to assist patients with HF to achieve these targets.
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Adsett et al. (2019) conducted a cohort in heart failure (n=140). Physical activity (≥150 min/week) and frequent program attendance (≥12 sessions) vs. Lower physical activity and infrequent attendance was evaluated on change in 6-min walk distance (6MWD) at 12 weeks (OR 3.8, 95% CI 1.3-11.5). Being physically active (OR 3.8; 95% CI 1.3-11.5) and frequent program attendance (OR 2.7; 95% CI 1.2-5.9) were associated with significant improvements in 6-minute walk distance at 12 weeks.
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