Key result
Low renin essential hypertension is associated with reduced resting sympathetic nerve activity and suppressed responsiveness to postural and tyramine stimulation compared to normal renin hypertension.
Cross-Sectional
p-value: p=<0.01
Patients with low renin essential hypertension exhibit reduced resting sympathetic nerve activity and suppressed responsiveness to stimulation, which may be secondary to water-sodium balance changes.
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Should not yet change hypertension management; leaves open sympathetic-targeted interventions in low-renin subtypes.
Iimura et al. (1979) conducted a cross-sectional in Low renin essential hypertension. Low renin essential hypertension vs. Normal renin essential hypertension and normotensive subjects was evaluated on Basal values of plasma noradrenaline (p=<0.01). Low renin essential hypertension is associated with reduced resting sympathetic nerve activity and suppressed responsiveness to postural and tyramine stimulation compared to normal renin hypertension.
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