Palliative status of patients with chronic heart failure: relationship with body composition parameters, clinical and laboratory parameters

Objective: to determine the relationship between parameters body composition, clinical status, laboratory parameters and severity of painful symptoms in patients with chronic heart failure. Materials and methods : the study involved 298 patients with CHF. The body composition was assessed: the presence of sarcopenia and obesity (with the calculation of the muscle mass index IMM/BMI), functional class, left ventricular ejection fraction, markers galectin-3, hsСRP, Na-proBNP, Bartel index. A 10-point Edmont scale was used to assess the severity of painful symptoms. A factor analysis was performed, as well as a Pearson correlation analysis. Results: the study revealed 5 components: A factor of adequacy of muscle functions, a factor of systolic dysfunction, a factor of impaired functional status, a factor of functional activity, and an age factor. The conducted correlation analysis showed the presence of links between the components and the severity of painful symptoms of moderate and mild severity. Conclusion: the body composition of patients is associated with the severity of painful symptoms in patients with CHF who need palliative care. It is necessary to take into account body composition when developing algorithms for managing patients with CHF at the stage of palliative care.