Why the study?
Is the disturbance of glucose tolerance in recent myocardial infarction a specific effect of the infarction or a non-specific stress response?
Is the disturbance of glucose tolerance in recent myocardial infarction a specific effect of the infarction or a non-specific stress response?
Glucose tolerance abnormalities during acute myocardial infarction are likely a non-specific stress response rather than indicative of latent diabetes.
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Glucose intolerance in acute MI likely reflects stress rather than diabetes; supports non-specific response but needs prospective confirmation.
Summary Intravenous glucose tolerance tests were carried ont on forty patients with recent myocardial infarction and thirty-nine matched controls with recent bone injury. Abnormal results were detected in 77·5% of cardiac patients and 68% controls. When tests were repeated after acute stress factors had settled, normal results were obtained in 85% of thirty-three cardiac subjects and 84% of thirty-eight controls. It is concluded that the disturbance of glucose tolerance in myocardial infarction is a non-specific stress effect and should not be regarded as necessarily indicating a latent diabetic tendency.
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Donald Pearson (1971) studied this question.
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