Key result
C-reactive protein levels were associated with subclinical atherosclerosis in the femoral artery (r=0.14, P=0.010) and antibody titres to ox-LDL (r=0.19, P<0.001) in healthy 58-year-old men.
Why the study?
Are CRP levels associated with subclinical atherosclerosis and antibodies to Ox-LDL in healthy men?
Cross-Sectional (n=391)
Are CRP levels associated with subclinical atherosclerosis and antibodies to Ox-LDL in healthy men?
Effect estimate: r = 0.14
p-value: p=0.010
In healthy 58-year-old men, CRP levels are associated with femoral atherosclerosis and Ox-LDL antibodies, though the atherosclerosis association is confounded by traditional cardiovascular risk factors.
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CRP-femoral atherosclerosis association may reflect confounding; leaves open independent inflammatory role in subclinical disease.
Hulthe et al. (2001) conducted a cross-sectional in Healthy (n=391). C-reactive protein (CRP) levels was evaluated on Ultrasound-assessed subclinical atherosclerosis in the femoral artery (r = 0.14, p=0.010). C-reactive protein levels were associated with subclinical atherosclerosis in the femoral artery (r=0.14, P=0.010) and antibody titres to ox-LDL (r=0.19, P<0.001) in healthy 58-year-old men.
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