Key result
During a 1986 outbreak of enterovirus 71 in Australia, 51% of hospitalized patients (33 of 65) had central nervous system involvement, highlighting meningoencephalitis as a major cause of morbidity.
Observational (n=114)
Enterovirus 71 infection can cause significant neurologic and respiratory morbidity, particularly meningoencephalitis in infants and young children, in addition to hand, foot and mouth disease.
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Warrants clinical awareness of neurologic risks in EV71; leaves open need for prospective studies on prevention.
Gilbert et al. (1988) conducted an observational in Enterovirus 71 infection (n=114). Enterovirus 71 infection was evaluated on Clinical manifestations including central nervous system involvement. During a 1986 outbreak of enterovirus 71 in Australia, 51% of hospitalized patients (33 of 65) had central nervous system involvement, highlighting meningoencephalitis as a major cause of morbidity.
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