Population
14 children with culture-proven, EV71-induced neurological disease during an outbreak of hand, foot, and…
Design
Case_series
Authors
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Raises awareness of long-term EV71 sequelae; challenges prior pathogenesis models and leaves open immunomodulatory trials.
In an EV71 outbreak in Western Australia, immunopathology appeared to be a major factor in the pathogenesis of neurological disease, contrasting with previous epidemics.
McMinn et al. (2001) studied this question.
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