Key result
Metoprolol succinate CR/XL provides stable 24-hour beta-1 blockade and is recommended for extensive use in clinical practice for treating arterial hypertension, coronary heart disease, and chronic heart failure.
Why the study?
To systematize current data on β-adrenoblockers used in cardiovascular diseases and analyze study results with a focus on metoprolol succinate CR/XL.
This review summarizes current international and Russian guidelines and evidence supporting the extensive use of metoprolol succinate CR/XL across various cardiovascular diseases.
Answers are grounded in this paper and cite their sources.
Supports metoprolol succinate per guidelines in hypertension, CHD, and HF; leaves open need for comparative RCTs.
The objective of this review was to systematize current data on the -adrenoblockers (-ABs) used in the treatment of cardiovascular diseases and to analyze the results of studies performed with a focus on metoprolol succinate controlled release/extended release (CR/XL) formulation. The article addresses issues related to pharmacological features of metoprolol succinate CR/XL, the use of -AB in arterial hypertension, coronary heart disease, chronic heart failure, and cardiac arrhythmias based on international and Russian clinical guidelines. Results of randomized clinical trials evaluating the efficacy of metoprolol succinate CR/XL are presented. In preparing the literature review, a review of publications over the past 34 years in the MEDLINE/PubMed, Scopus, Cochrane Library, eLIBRARY, and Google Scholar databases was performed. The presented data indicate the need for more extensive use of -ABs, including metoprolol succinate CR/XL, in clinical practice.
No takes yet. Share an insight, caveat, or question.
М. Г. Бубнова (2022) conducted a review in Cardiovascular diseases (arterial hypertension, coronary heart disease, chronic heart failure, cardiac arrhythmias). Metoprolol succinate CR/XL was evaluated. Metoprolol succinate CR/XL provides stable 24-hour beta-1 blockade and is recommended for extensive use in clinical practice for treating arterial hypertension, coronary heart disease, and chronic heart failure.
Synapse has enriched 10 related papers. Consider them for comparative context: