Key result
Right ventricular pacing is associated with a low incidence of left ventricular dysfunction in patients with congenital complete atrioventricular block, even after more than 10 years of pacing.
Why the study?
Does long-term right ventricular pacing cause left ventricular dysfunction in children with congenital complete atrioventricular block?
Does long-term right ventricular pacing cause left ventricular dysfunction in children with congenital complete atrioventricular block?
Long-term right ventricular pacing is associated with a low incidence of left ventricular dysfunction in children with congenital complete AV block, supporting its continued use as an acceptable first-line therapy.
May support continued RV pacing in congenital complete AV block; leaves open need for prospective confirmation.
Evaluation of: Kim JJ, Friedman RA, Eidem BW et al. Ventricular function and long-term pacing in children with congenital complete atrioventricular block. J. Cardiovasc. Electrophysiol. 18, 373–377 (2007).Cardiac pacing from right ventricular apex and free wall positions alters inter- and intraventricular impulse conduction and distorts biventricular contractility. In patients with congenital atrioventricular block there is a risk for heart failure, mitral regurgitation, syncope and sudden death before pacemaker implantation, and development of heart failure or mitral regurgitation after long-term ventricular pacing. Recently, selective site pacing has been recommended as a therapeutic option in patients with complete atrioventricular block. The evaluated study demonstrated that left ventricular dysfunction in patients with congenital complete atrioventricular block is rare, even in those who have been paced for more than 10 years. Right ventricular apex pacing and prolonged QRS duration may be associated with decreased ventricular function over time. At this time, with such a low incidence of cardiac dysfunction, right ventricular pacing should be considered an acceptable first-line therapy in this population.
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Abolfath Alizadeh (2007) conducted an editorial in Congenital complete atrioventricular block. Right ventricular pacing was evaluated on Left ventricular dysfunction. Right ventricular pacing is associated with a low incidence of left ventricular dysfunction in patients with congenital complete atrioventricular block, even after more than 10 years of pacing.
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