Why the study?
Does adiposity affect endothelial function, vascular measurements, and metabolic biomarkers in children aged 7-18 years?
Population
105 children aged 7-18 years, including 85 with adiposity and 20 normal-weight controls.
Comparison
Adiposity vs Normal-weight controls
Design
Cross-sectional
Authors
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Adiposity may impair vascular function in hypertensive children; hypothesis-generating and requires longitudinal studies before clinical implications.
Does adiposity affect endothelial function, vascular measurements, and metabolic biomarkers in children aged 7-18 years?
Adiposity in children is associated with early surrogate markers of vascular dysfunction, including reduced flow-mediated dilation and increased pulse wave velocity, particularly in the presence of hypertension.
Lo et al. (2018) studied this question.
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