Key result
Electrically induced atrial premature depolarizations in rabbit sinoatrial preparations resulted in four basic patterns of alteration in SA nodal rhythm, depending on the timing of the APD.
Population
Rabbit sinoatrial (SA) preparations
Design
Preclinical
Authors
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May warrant caution interpreting atrial electrograms as SA nodal proxies post-APD; leaves open direct nodal mapping in arrhythmia models.
Extracellular records of atrial activity may not accurately reflect sinoatrial nodal events following atrial premature depolarizations.
Klein et al. (1973) studied Atrial premature depolarizations. Electrically induced atrial premature depolarizations (APDs) was evaluated on Alteration in the SA nodal rhythm. Electrically induced atrial premature depolarizations in rabbit sinoatrial preparations resulted in four basic patterns of alteration in SA nodal rhythm, depending on the timing of the APD.
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