Why the study?
To evaluate whether prevalent CVD is associated with global electrical heterogeneity (GEH), whether sex differences exist in GEH, and whether sex modifies the association of prevalent CVD with GEH.
Are there sex differences in the association between prevalent cardiovascular disease and global electrical heterogeneity in African-Americans?
Population
3679 Jackson Heart Study participants with analysable ECGs
Comparison
Prevalent CVD vs CVD-free, stratified by sex
Design
Cross-sectional cohort study
Authors
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Sex differences in ECG heterogeneity with prevalent CVD may warrant sex-aware interpretation in African-Americans; leaves open utility for risk stratification.
Are there sex differences in the association between prevalent cardiovascular disease and global electrical heterogeneity in African-Americans?
There are significant sex differences in the vectorcardiographic electrical signature of cardiovascular disease among African-Americans, highlighting the influence of sex on cardiac repolarization.
Pollard et al. (2021) studied this question.
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