Key result
Global electrical heterogeneity, specifically QRST-angle, was a strong independent predictor of cardiovascular mortality in men (HR 3.44; 95% CI 2.12-5.36) and women (HR 2.47; 95% CI 1.37-4.45).
Why the study?
Do ECG/VECG markers of global electrical heterogeneity predict cardiovascular and all-cause mortality in men and women?
Population
1,751 adults (840 men, 911 women), average age 63 years
Design
Cohort
Follow-up
average 14 years
Authors
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ECG heterogeneity markers may refine long-term CVD/mortality risk stratification; leaves open prospective validation before clinical adoption.
Cohort (n=1,751)
Do ECG/VECG markers of global electrical heterogeneity predict cardiovascular and all-cause mortality in men and women?
Hazard Ratio: 3.44 (95% CI 2.12–5.36)
Global electrical heterogeneity markers, particularly QRST-angle, provide independent prognostic value for cardiovascular mortality risk stratification in both men and women.
Lipponen et al. (2018) conducted a cohort in Cardiovascular mortality risk (n=1,751). Global electrical heterogeneity (e.g., QRST-angle) was evaluated on Cardiovascular mortality (HR 3.44, 95% CI 2.12-5.36). Global electrical heterogeneity, specifically QRST-angle, was a strong independent predictor of cardiovascular mortality in men (HR 3.44; 95% CI 2.12-5.36) and women (HR 2.47; 95% CI 1.37-4.45).
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