Key result
Adults with complex congenital heart disease had statistically significant differences in functional class distribution across multiple indices compared to those with simple or moderate disease.
Observational (n=456)
No
Functional clinical status and physical activity limitation should be the main criteria for assessing health in adults with congenital heart disease, regardless of anatomical complexity.
Supports prioritizing functional status assessment in adult CHD care; leaves open whether complexity adds independent prognostic value.
The aim — to estimate the severity and clinical functional status in adults with congenital heart disease (ACHD).Materials and methods. The study included 456 consecutive adults with CHD who were admitted to Scientific and Practical Medical Center of Pediatric Cardiology and Cardiac Surgery of Health Ministry of Ukraine (Kyiv, Ukraine) from January 1, 2014 to December 31, 2015. The average age was 27.4 ± 0.5 years (from 18 to 67 years), men were 225 (49.3 %), women — 231 (50.7 %). The severity of CHD was assessed using 2 scales: the severity of primary diagnosis (scale 1), and Disease severity index (scale 2); the functional status — by Ability index, (scale 3), Congenital heart disease functional index (scale 4) and NYHA functional class (FC) of heart failure (scale 5).Results and discussion. There were statistically significant differences in FC I, III and IV between complex and simple CHD, in FC II, III and IV between complex and moderate CHD and in FC I, II between moderate and simple CHD by Scale 3. There were statistically significant differences in FC II, IV and V between complex and simple CHD, in FC IIV between complex and moderate CHD and in FC I — III between moderate and simple CHD by Scale 4. The comparative analysis of scale 5 and scale 1 presented the same statistically significant differences compared to scale 3.Conclusions. The preserved functional clinical status of adults with congenital heart disease, absence of limitation of physical activity in everyday life, the opportunity to be engaged in work or study full day should be the main criteria for assessing the health in this cohort of patients, despite the complexity of congenital heart disease, previous surgical and/or percutaneous interventions.
No takes yet. Share an insight, caveat, or question.
І. G. Lebid (2018) conducted an observational in Congenital heart disease (n=456). Complex congenital heart disease vs. Simple or moderate congenital heart disease was evaluated on Functional status assessed by Ability index, Congenital heart disease functional index, and NYHA functional class. Adults with complex congenital heart disease had statistically significant differences in functional class distribution across multiple indices compared to those with simple or moderate disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: